GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs12220238 | 1 | rs11000922 | chr10:75969305 | ADK | chr10:75910965-76469059:+ | 0.33 | 4.81 | 2.14E-6 | Soluble interleukin-2 receptor subunit alpha |
| BLCA | cis | rs12220238 | 1 | rs11000922 | chr10:75969305 | AP3M1 | chr10:75880016-75910826:- | 0.33 | 4.18 | 3.68E-5 | Soluble interleukin-2 receptor subunit alpha |
| BLCA | cis | rs12220238 | 1 | rs11000922 | chr10:75969305 | MYST4 | chr10:76586379-76792639:+ | 0.25 | 3.99 | 7.97E-5 | Soluble interleukin-2 receptor subunit alpha |
| BLCA | cis | rs12220238 | 1 | rs11000924 | chr10:75972311 | ADK | chr10:75910965-76469059:+ | 0.3 | 4.62 | 5.23E-6 | Soluble interleukin-2 receptor subunit alpha |
| BLCA | cis | rs12220238 | 1 | rs11000925 | chr10:75972601 | ADK | chr10:75910965-76469059:+ | 0.3 | 4.62 | 5.23E-6 | Soluble interleukin-2 receptor subunit alpha |
| BLCA | cis | rs12220238 | 1 | rs11000930 | chr10:75982982 | ADK | chr10:75910965-76469059:+ | -0.35 | -4.99 | 9.05E-7 | Soluble interleukin-2 receptor subunit alpha |
| BLCA | cis | rs12220238 | 1 | rs11000930 | chr10:75982982 | AP3M1 | chr10:75880016-75910826:- | -0.38 | -4.72 | 3.26E-6 | Soluble interleukin-2 receptor subunit alpha |
| BLCA | cis | rs12220238 | 1 | rs11000930 | chr10:75982982 | MYST4 | chr10:76586379-76792639:+ | -0.26 | -4.11 | 4.92E-5 | Soluble interleukin-2 receptor subunit alpha |
| BLCA | cis | rs12220238 | 1 | rs11000930 | chr10:75982982 | VDAC2 | chr10:76970563-76991204:+ | -0.31 | -4.32 | 2.0E-5 | Soluble interleukin-2 receptor subunit alpha |
| BLCA | cis | rs12220238 | 1 | rs11000931 | chr10:75984800 | ADK | chr10:75910965-76469059:+ | -0.25 | -3.9 | 0.000115 | Soluble interleukin-2 receptor subunit alpha |
| BLCA | cis | rs12220238 | 1 | rs11000936 | chr10:75992383 | ADK | chr10:75910965-76469059:+ | 0.28 | 4.24 | 2.81E-5 | Soluble interleukin-2 receptor subunit alpha |
| BLCA | cis | rs12220238 | 1 | rs11000941 | chr10:76018301 | ADK | chr10:75910965-76469059:+ | 0.31 | 4.56 | 7.04E-6 | Soluble interleukin-2 receptor subunit alpha |
| BLCA | cis | rs12220238 | 1 | rs11000941 | chr10:76018301 | AP3M1 | chr10:75880016-75910826:- | 0.3 | 3.85 | 0.000138 | Soluble interleukin-2 receptor subunit alpha |
| BLCA | cis | rs7927771 | 1 | rs11039255 | chr11:47495746 | C1QTNF4 | chr11:47611216-47615961:- | -0.29 | -5.52 | 6.24E-8 | Subjective well-being |
| BLCA | cis | rs7927771 | 1 | rs11039390 | chr11:47796295 | C1QTNF4 | chr11:47611216-47615961:- | -0.3 | -5.65 | 3.22E-8 | Subjective well-being |